Developmental effects: oestrogen-induced vaginal changes and organotin-induced adipogenesis
نویسندگان
چکیده
منابع مشابه
Oestrogen-Induced Multicomponent Protein
1. The process by which the egg-yolk protein precursor vitellogenin is biosynthesized, assembled and secreted by Xenopus laevis (South African clawed toad) liver was studied. It was previously shown in other laboratories that vitellogenin contains the two egg-yolk proteins lipovitellin (mol.wt. 140000) and phosvitin (mol.wt. 35000). 2. Evidence is presented which shows that Xenopus liver micros...
متن کاملOestrogen-induced apoptosis in colonocytes expressing oestrogen receptor beta.
Epidemiological studies of postmenopausal hormone replacement therapy show a reduction in the risk of developing colon cancer, and animal studies using 17beta-oestradiol (E(2)) demonstrate a decreased incidence of chemically-induced colon cancer. Using the colon cancer cell line, COLO205, we found that E(2) induced a dose-dependent increase in DNA fragmentation and nuclear condensation, signifi...
متن کاملCellular and molecular aspects of organotin-induced thymus atrophy.
1. Organotin compounds, di-n-butyltin dichloride (DBTC) in particular, have been shown to cause thymus atrophy in the rat. 2. DBTC-induced thymus atrophy results from a depletion of small CD4+CD8+ thymocytes which is caused by a diminished production of immature CD4-CD8+ and CD4+CD8+ thymoblasts. 3. DBTC inhibits the activation, but not the differentiation of immature CD4-CD8+ thymocytes in vit...
متن کاملEffects of Icariin on Histomorphometric Changes of Testis and Prostate Induced by Acrylamide in Mice
Background and Aims: This study aimed to observe the effect of Icariin on histomorphometric changes of testis and prostate induced by Acrylamide. Materials and Methods: Male mice were divided into four groups (n=8): A is the control group and does not get any treatment, B is the sham group and only received drinking water. C group received Acrylamide 10 mg/kg. D group received Acrylamide 15 mg...
متن کاملDehydroepiandrosterone treatment attenuates oestrogen-induced pituitary hyperplasia.
The physiological importance of and therapeutic interest in dehydroepiandrosterone (DHEA) has been predominantly in relation to its action as an inhibitor of the promotion and progression of several kinds of tumours, including those of breast, prostate, lung, colon, liver and skin tissues. The aim of the present study was to determine the role of DHEA in diethylstilboestrol (DES)-induced pituit...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: International Journal of Andrology
سال: 2008
ISSN: 0105-6263,1365-2605
DOI: 10.1111/j.1365-2605.2008.00863.x